Forsyth R D, Cole P, Shephard R J
J Appl Physiol Respir Environ Exerc Physiol. 1983 Sep;55(3):860-5. doi: 10.1152/jappl.1983.55.3.860.
Nasal airflow resistances were studied in 20 healthy subjects at rest, with exercise, and during recovery from exercise. Resistances were first measured under resting conditions. As a basis for comparison 0.1% xylometazoline was applied by insufflation; it reduced nasal resistance by an average of 49%. On a subsequent occasion, the degree and time course of changes in resistance were measured 1) during 5-min exercise bouts at rest 25, 50, and 75% of predicted maximum O2 intake (VO2max), 2) during 5-, 10-, and 15-min exercise bouts at 50% of VO2max, and 3) during recovery from exercise. Resistance decreased with intensity but not duration of exercise; an initial sudden decrease was followed by a more gradual but progressive decrease, which continued for several minutes following vigorous short duration exercise. Thus following 5 min of effort at 75% of VO2max, resistance reached a nadir (46% fall) 5 min after cessation of exercise. Recovery of preexercise values required 5 min after 5 min of exercise at 25% of VO2max and 10 min after 5 min of exercise at 50% of VO2max. Some decrease persisted 15 min after 5 min of exercise at 75% of VO2max.
对20名健康受试者在静息状态、运动时以及运动恢复过程中的鼻腔气流阻力进行了研究。首先在静息条件下测量阻力。作为比较的基础，通过吹入法应用0.1%的赛洛唑啉；它使鼻腔阻力平均降低了49%。在随后的一次实验中，测量了阻力变化的程度和时间进程：1）在静息状态下进行5分钟运动，运动强度分别为预测最大摄氧量（VO2max）的25%、50%和75%时；2）在VO2max的50%强度下分别进行5分钟、10分钟和15分钟的运动时；3）在运动恢复过程中。阻力随运动强度降低，但不随运动持续时间降低；最初会突然下降，随后是更缓慢但持续的下降，在短时间剧烈运动后的几分钟内这种下降仍会持续。因此，在以VO2max的75%强度运动5分钟后，运动停止5分钟时阻力降至最低点（下降46%）。在以VO2max的25%强度运动5分钟后，恢复到运动前的值需要5分钟；在以VO2max的50%强度运动5分钟后，则需要10分钟。在以VO2max的75%强度运动5分钟后，15分钟时仍有一些阻力下降持续存在。
