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人类细胞遗传学的发展:一篇百科全书式的文章。III. 1956年后的第二个十年:显带技术。

Evolution of human cytogenetics: an encyclopedic essay. III. The second decade after 1956: banding techiques.

作者信息

Srivastava P K, Lucas F V

出版信息

J Genet Hum. 1976 Dec;24(4):337-50.

PMID:66304
Abstract

Unequivocal establishment of the correct diploid chromosome number in 1956 started the modern era of human cytogenetics. The next impetus came when the peripheral blood leukocyte culture technique for the chromosome preparation was described in 1960. Discovery of special staining procedures - banding techniques - in early seventies not only saved it from early senescence but played decisive roles in broadening the horizons of modern human cytogenetics.

摘要

1956年明确确立正确的二倍体染色体数目开启了人类细胞遗传学的现代纪元。1960年描述了用于染色体制备的外周血白细胞培养技术,这带来了下一个推动力。70年代初特殊染色程序——显带技术的发现不仅使其免于过早衰落,而且在拓宽现代人类细胞遗传学的视野方面发挥了决定性作用。

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