Fan K J
J Natl Med Assoc. 1983 Aug;75(8):765-9.
A postmortem histopathological study was done in 233 pineal glands of black patients. Among them, 70 percent showed microscopic evidence of calcification in the pineal parenchyma. The frequency of calcification increased with age. However, the severity of calcification reached the peak in the 60 to 69 year old age group and then gradually declined. As compared to males, females had slightly higher frequency and reached the peak of severity in younger age groups. When pineal calcification was compared among patients with various malignancies, a higher frequency and more severe calcification were observed in patients with carcinoma of the prostate and the pancreas. A lower frequency and less severe calcification were observed in patients with carcinoma of the breast and the cervix. The results of this study emphasize the important role of sex hormone in genesis of pineal calcification.
对233例黑人患者的松果体进行了尸检组织病理学研究。其中,70%的松果体实质有微观钙化证据。钙化频率随年龄增加。然而,钙化严重程度在60至69岁年龄组达到峰值,然后逐渐下降。与男性相比,女性钙化频率略高,且在较年轻年龄组达到严重程度峰值。在比较各种恶性肿瘤患者的松果体钙化情况时,前列腺癌和胰腺癌患者的钙化频率更高、程度更严重。乳腺癌和宫颈癌患者的钙化频率较低、程度较轻。本研究结果强调了性激素在松果体钙化发生中的重要作用。