Dominioni L, Alexander J W, Ogle C K, Mayfield G, Silberstein E B
J Trauma. 1983 Oct;23(10):911-5. doi: 10.1097/00005373-198310000-00012.
The in vivo chemotactic response of Indium-111 labelled polymorphonuclear leukocytes (PMNL) and their body compartment distribution have been studied in burned (30% TBSA full-thickness burn) and normal guinea pigs. The in vivo chemotactic response to FMLP 10(-5) M and to zymosan-activated serum of the burned PMNL was not significantly different from that of normal PMNL. However, the burned PMNL leave the circulation more rapidly and localize in the burn area and in the liver to a greater extent. No evidence of increased destruction of burned PMNL by the spleen or by the lungs was found.
已对铟 - 111标记的多形核白细胞（PMNL）在烧伤（30% 体表面积全层烧伤）和正常豚鼠体内的趋化反应及其在体内各腔室的分布进行了研究。烧伤的PMNL对10(-5) M的FMLP和酵母聚糖激活血清的体内趋化反应与正常PMNL的趋化反应无显著差异。然而，烧伤的PMNL离开循环系统的速度更快，并且在烧伤区域和肝脏中的定位程度更高。未发现脾脏或肺部对烧伤的PMNL破坏增加的证据。
