Rozenberg O A, Bekreneva V Iu, Loshakova L V, Rezvaia S P, Davidenkova E F
Vopr Onkol. 1983;29(10):56-60.
The trapping of liposomes from native phospholipids by tumor cells was found to be 2-6 times that of egg lecithin vesicles. These differences in the level of incorporation of the two types of liposomes in the course of incubation with ascitic lymphocytic leukemia cells NKLy/LL seem to be due to the different mechanisms of their utilization. Egg lecithin liposomes are trapped via endocytosis which is not highly pronounced in these cells, whereas vesicles from target-cell phospholipids are incorporated by fusion mechanism.
研究发现，肿瘤细胞从天然磷脂中捕获脂质体的能力是卵磷脂囊泡的2至6倍。在与腹水淋巴细胞白血病细胞NKLy/LL孵育过程中，这两种脂质体的摄取水平存在差异，这似乎是由于它们不同的利用机制所致。卵磷脂脂质体通过内吞作用被捕获，而内吞作用在这些细胞中并不十分明显，而来自靶细胞磷脂的囊泡则通过融合机制被摄取。
