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溴隐亭对泌乳母猪促黄体生成素水平的影响:催乳素和哺乳刺激的抑制作用证据。

The effect of bromocriptine on luteinizing hormone levels in the lactating sow: evidence for a suppressive action by prolactin and the suckling stimulus.

作者信息

Bevers M M, Willemse A H, Kruip T A

出版信息

Acta Endocrinol (Copenh). 1983 Nov;104(3):261-5. doi: 10.1530/acta.0.1040261.

Abstract

Lactating sows (5 per group) were given no treatment or 10 mg bromocriptine orally twice daily from day 14 to 22 after parturition. Both groups were weaned at day 22. Frequent bleedings at 10 min intervals for 6 h were performed at 12, 16, 20 and 24 days after parturition. Prolactin and LH levels were measured in the collected blood samples by radioimmunoassays. Reduction of Prl by bromocriptine increased mean LH levels significantly and a further significant increase was observed after weaning. From the results it is concluded that in the lactating sow both Prl per se and the suckling stimulus are involved in suppression of LH levels.

摘要

泌乳母猪(每组5头)在分娩后第14天至22天,一组不做处理,另一组每天口服10毫克溴隐亭,每日两次。两组均在第22天断奶。在分娩后第12、16、20和24天,每隔10分钟频繁采血6小时。通过放射免疫分析法测定采集血样中的催乳素和促黄体生成素水平。溴隐亭降低催乳素水平显著提高了促黄体生成素的平均水平,断奶后观察到促黄体生成素水平进一步显著升高。从结果得出结论,在泌乳母猪中,催乳素本身和哺乳刺激均参与促黄体生成素水平的抑制。

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