Reuber H, Vollrath L
Acta Anat (Basel). 1983;117(2):121-7. doi: 10.1159/000145777.
Previous studies have yielded equivocal results concerning the 24-hour rhythmicity of mitotic activity in the rat pineal. The aim of the present study was to re-investigate this problem by carrying out three separate 24-hour experiments on alternate days. The results obtained confirm previous findings showing that in the pineal gland of adults mitotic activity is low. On average 22.3 mitotic figures of pinealocytes are seen per pineal gland, corresponding to a mitotic index of 0.2-0.6/1,000 pinealocytes. Mitotic activity is distinctly higher at daytime than at night. The timing of the peaks and troughs differs slightly from experiment to experiment. The majority of observations now indicate that in the rat pineal gland mitotic activity is higher at day time than at night.
先前的研究关于大鼠松果体有丝分裂活动的24小时节律性得出了模棱两可的结果。本研究的目的是通过在隔天进行三项独立的24小时实验来重新研究这个问题。获得的结果证实了先前的发现，即成年松果体中有丝分裂活动较低。每个松果体平均可见22.3个松果体细胞的有丝分裂图，对应于0.2 - 0.6/1000个松果体细胞的有丝分裂指数。有丝分裂活动在白天明显高于夜间。每次实验中高峰和低谷的时间略有不同。现在大多数观察结果表明，大鼠松果体中有丝分裂活动在白天高于夜间。
