Armstrong B K, Margetts B M, Masarei J R, Hopkins S M
Am J Epidemiol. 1983 Nov;118(5):651-8. doi: 10.1093/oxfordjournals.aje.a113676.
Coronary risk factor levels (height, weight, blood pressure, serum total cholesterol, high density lipoprotein (HDL) cholesterol, serum apo-HDL, physical activity, and smoking and drinking habits) were measured in 177 Italian migrants to Australia aged 20-79 years and 176 age-matched native-born Australians of Australian, British or New Zealand parentage. The Italian men had a lower mean systolic and diastolic blood pressure (125.0/79.8 mmHg) than the Australian men (129.4/82.3 mmHg), but Italians of both sexes had higher mean body mass indices (2.8 and 2.9 g/cm2) than Australians (2.4 and 2.5 g/cm2) and Italian women had a significantly lower mean serum HDL cholesterol concentration (1.16 mmol/liter) than Australian women (1.34 mmol/liter). The blood pressure differences between Italians and Australians were increased by adjustment of the means for differences between the two groups in age and obesity. There were slightly more current smokers and drinkers in Italian men than in Australian men; the opposite was true in women. Risk factor levels in Italians were influenced little by duration of residence in Australia. Mortality from ischemic heart disease in Italians in Italy and Italian migrants to Australia is between one third and two thirds that in native-born Australians. The small differences in coronary risk factors observed in this study appear insufficient to explain differences in ischemic heart disease mortality of this size.
对177名年龄在20至79岁之间的意大利裔澳大利亚移民以及176名年龄匹配、父母为澳大利亚、英国或新西兰裔的澳大利亚本土居民，测量了其冠心病风险因素水平（身高、体重、血压、血清总胆固醇、高密度脂蛋白（HDL）胆固醇、血清载脂蛋白-HDL、身体活动以及吸烟和饮酒习惯）。意大利男性的平均收缩压和舒张压（125.0/79.8 mmHg）低于澳大利亚男性（129.4/82.3 mmHg），但意大利男女的平均体重指数均高于澳大利亚人（分别为2.8和2.9 g/cm²，澳大利亚人分别为2.4和2.5 g/cm²），且意大利女性的平均血清HDL胆固醇浓度（1.16 mmol/升）显著低于澳大利亚女性（1.34 mmol/升）。通过对两组年龄和肥胖差异进行均值调整后，意大利人和澳大利亚人之间的血压差异有所增大。意大利男性中当前吸烟者和饮酒者略多于澳大利亚男性；女性情况则相反。意大利人的风险因素水平受在澳大利亚居住时间的影响较小。在意大利的意大利人以及意大利裔澳大利亚移民的缺血性心脏病死亡率是澳大利亚本土居民的三分之一至三分之二。本研究中观察到的冠心病风险因素的微小差异似乎不足以解释如此大的缺血性心脏病死亡率差异。
