Yasuhara M, Kuramoto T, Hoshita T, Itoga E, Kito S
Steroids. 1978 Mar;31(3):333-45. doi: 10.1016/0039-128x(78)90047-8.
The bile alcohols present in the feces of a patient with cerebrotendinous xanthomatosis were studied. Three bile alcohols which are different from any known natural bile alcohol were isolated as minor components of the fecal bile alcohol fraction. The structures of these compounds were established as 5 beta-cholestane-3 alpha, 7 alpha, 12 alpha, 23 beta-tetrol, 5 beta-cholestane-3 alpha, 7 alpha, 12 alpha, 24 alpha-tetrol, and 5 beta-cholestane-3 alpha, 7 alpha, 12 alpha, 24 beta-tetrol by comparison with synthetic samples.
对脑腱性黄瘤病患者粪便中的胆汁醇进行了研究。从粪便胆汁醇组分的次要成分中分离出三种与任何已知天然胆汁醇不同的胆汁醇。通过与合成样品比较,确定这些化合物的结构为5β-胆甾烷-3α,7α,12α,23β-四醇、5β-胆甾烷-3α,7α,12α,24α-四醇和5β-胆甾烷-3α,7α,12α,24β-四醇。