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基底神经节、丘脑及深部白质病变:对语言功能的不同影响。

Lesions of the basal ganglia, thalamus, and deep white matter: differential effects on language functions.

作者信息

Wallesch C W, Kornhuber H H, Brunner R J, Kunz T, Hollerbach B, Suger G

出版信息

Brain Lang. 1983 Nov;20(2):286-304. doi: 10.1016/0093-934x(83)90046-9.

DOI:10.1016/0093-934x(83)90046-9
PMID:6640281
Abstract

Forty-five patients with unilateral demarcated vascular lesions in the basal ganglia, the thalamus and the deep white matter were investigated with an "aphasia battery." Patients with basal ganglia lesions performed worse than both other groups in tests of articulation, syntax, and lexical functions. The deficit of patients with basal ganglia lesions on all expressive language modalities was lateralized to the left hemisphere. Patients with left thalamic lesions showed impairments of speech fluency and in the Token Test. Patients with white matter lesions alone showed no effect of laterality in tests of language functions. The results are discussed on the basis of a recent theory of the participation of the deep nuclei in language processing.

摘要

对45例基底神经节、丘脑和深部白质有单侧界限性血管病变的患者进行了“失语症成套测验”。基底神经节病变患者在发音、句法和词汇功能测试中的表现比其他两组都差。基底神经节病变患者在所有表达性语言模式上的缺陷都偏向于左半球。左侧丘脑病变患者表现出言语流畅性受损和在词语辨别测验中的缺陷。单纯白质病变患者在语言功能测试中未表现出偏侧性影响。根据深部核团参与语言加工的最新理论对结果进行了讨论。

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