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Presynaptic modulation of the release of dopamine from striatal synaptosomes: differences in the effects of high K+ stimulation, methamphetamine and nicotinic drugs.

作者信息

Takano Y, Sakurai Y, Kohjimoto Y, Honda K, Kamiya H O

出版信息

Brain Res. 1983 Nov 21;279(1-2):330-4. doi: 10.1016/0006-8993(83)90204-4.

Abstract

We examined the effects of nicotinic drugs on the metabolites of [3H]dopamine (DA) released from rat striatal synaptosomes in comparison with the effects of high K+ and methamphetamine stimulation. The pattern of outflow of [3H]DA and its metabolites induced by nicotine stimulants, acetylcholine (ACh), nicotine and lobeline, was different from that induced by high K+ and methamphetamine.

摘要

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