Curzi-Dascalova L, Flores-Guevara R, Guidasci S, Korn G, Monod N
Early Hum Dev. 1983 Oct;8(3-4):235-41. doi: 10.1016/0378-3782(83)90006-3.
The present study was carried out on 76 polygraphic recordings performed on 38 siblings of sudden infant death syndrome victims and on 38 control (2 days to 18 weeks old) infants. Each sibling corresponded to a control infant according to gender, gestational age at birth and postnatal age criteria. We found that in siblings as in controls, respiratory frequency (RF) was higher in active sleep (AS) compared to quiet sleep (QS) state (P less than 0.05 for 11-18 week siblings, p less than 0.01 for the other groups). During the transitional sleep (TS), RF was on an intermediate level (AS greater than TS greater than QS). There were no significant differences between RF of siblings compared to controls, except that RF during QS in 6-10 week control infants was higher than in siblings of the same age (P less than 0.05). We found a wide variability between RF of different individuals within all the age groups of siblings and of controls (P less than 0.001). However, a high correlation was usually noted between RF found in different sleep states: some infants (siblings or controls) breathed more rapidly and others more slowly in all states studied. In siblings, as previously described in other groups of normal infants, RF seems to be an individual characteristic. In addition, the present work shows that according to RF criterion, healthy siblings are similar to normal infants.
本研究对38名婴儿猝死综合征受害者的兄弟姐妹及38名对照婴儿（年龄在2天至18周之间）进行了76次多导睡眠图记录。根据性别、出生时的胎龄和出生后年龄标准，每个兄弟姐妹对应一名对照婴儿。我们发现，与对照组一样，兄弟姐妹在活跃睡眠（AS）状态下的呼吸频率（RF）高于安静睡眠（QS）状态（11 - 18周的兄弟姐妹P < 0.05，其他组P < 0.01）。在过渡睡眠（TS）期间，RF处于中间水平（AS > TS > QS）。与对照组相比，兄弟姐妹的RF没有显著差异，只是6 - 10周龄对照婴儿在QS期间的RF高于同龄的兄弟姐妹（P < 0.05）。我们发现，在兄弟姐妹和对照组的所有年龄组中，不同个体的RF存在很大差异（P < 0.001）。然而，通常在不同睡眠状态下发现的RF之间存在高度相关性：在所有研究状态下，一些婴儿（兄弟姐妹或对照组）呼吸较快，而另一些则较慢。与其他正常婴儿组之前的描述一样，在兄弟姐妹中，RF似乎是个体特征。此外，目前的研究表明，根据RF标准，健康的兄弟姐妹与正常婴儿相似。
