非肾素介导的肾血管性高血压：一种新综合征？
Non-renin-mediated renovascular hypertension: A new syndrome?
作者信息
Marks L S, Maxwell M H, Kaufman J J
出版信息
Lancet. 1977 Mar 19;1(8012):615-7. doi: 10.1016/s0140-6736(77)92054-2.
PMID:66424
Abstract
In two hypertensive patients with renal-artery stenosis, overactivity of the renin-angiotensin system was ruled out by investigations of renin and aldosterone concentrations and by the lack of a vasodepressor response to angiotensin blockade with saralasin. Nevertheless, hypertension was cured by renal revascularisation. The date suggest that there is a form of renovascular hypertension which is not mediated by the renin-angiotensin system.
摘要
在两名患有肾动脉狭窄的高血压患者中，通过对肾素和醛固酮浓度的检测以及缺乏对沙拉新（saralasin）阻断血管紧张素的降压反应，排除了肾素 - 血管紧张素系统的过度活跃。然而，通过肾血管重建术治愈了高血压。这些数据表明存在一种不由肾素 - 血管紧张素系统介导的肾血管性高血压形式。
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