Marcomichelakis J, Withers R, Newman G B, O'Brien K, Emanuel R
Int J Cardiol. 1983 Nov-Dec;4(4):405-19. doi: 10.1016/0167-5273(83)90190-0.
We obtained echocardiographic measurements of interventricular septal and posterior left ventricular wall thickness in 100 apparently normal subjects in whom there was no evidence or history of coronary artery disease, hypertension or prolapsing mitral valve. Subjects were divided into five age groups of 20-29, 30-39, 40-49, 50-59 and 60-70 years and there were 20 subjects in each group. Measurements of interventricular septum and posterior left ventricular wall thickness were made in each subject at both mitral and sub-mitral levels at the time of Q wave inscription, and the measurements were related to body surface area. The interventricular septum increased from a median of 8.3 mm in the age group 20-29 to 11.2 mm in the group 60-70, whereas the posterior left ventricular wall increased from 7.5 mm to 9.8 mm. The difference in the medians between the groups 20-29 and 60-70 was statistically significant for both interventricular septum and posterior left ventricular wall (P less than 0.02). Our data showed that interventricular septal, posterior left ventricular wall thickness measurements and their ratio should be related to age in order to assess their significance.
我们对100名明显正常的受试者进行了超声心动图测量，这些受试者无冠状动脉疾病、高血压或二尖瓣脱垂的证据或病史。受试者被分为五个年龄组，分别为20 - 29岁、30 - 39岁、40 - 49岁、50 - 59岁和60 - 70岁，每组20人。在Q波记录时，对每个受试者在二尖瓣和二尖瓣下水平测量室间隔和左心室后壁厚度，并将测量结果与体表面积相关联。室间隔厚度从20 - 29岁年龄组的中位数8.3毫米增加到60 - 70岁组的11.2毫米，而左心室后壁厚度从7.5毫米增加到9.8毫米。20 - 29岁组和60 - 70岁组之间室间隔和左心室后壁厚度中位数的差异具有统计学意义（P小于0.02）。我们的数据表明，为了评估其意义，室间隔、左心室后壁厚度测量及其比值应与年龄相关。
