Benson D M, Rifkin M D, Rose J L, Goldberg B B
Invest Radiol. 1983 Sep-Oct;18(5):459-62. doi: 10.1097/00004424-198309000-00011.
A physical basis was developed for an accurate noninvasive technique to differentiate malignant thyroid tumors from benign lesions based upon a frequency-dependent attenuation model. The research effort utilized RF waveform analysis via a minicomputer based digital processing system. Data collection was performed using a standard clinical B-Mode diagnostic instrument with a transducer specially designed for imaging the thyroid gland. Differences between the frequency spectra of the RF waveforms for benign and malignant pathologies could be demonstrated in accordance with the proposed model.
基于频率依赖衰减模型，开发了一种准确的非侵入性技术的物理基础，用于区分恶性甲状腺肿瘤与良性病变。研究工作通过基于小型计算机的数字处理系统利用射频波形分析。使用标准临床B型诊断仪器和专门设计用于甲状腺成像的换能器进行数据收集。根据所提出的模型，可以证明良性和恶性病变的射频波形频谱之间的差异。
