Maile C W, Moore A V, Ulreich S, Putman C E
Invest Radiol. 1983 Nov-Dec;18(6):495-9. doi: 10.1097/00004424-198311000-00002.
A radiographic-pathologic correlation study of adult leukemia patients was conducted to determine the frequency and radiographic appearance of leukemic involvement and related complications within the chest. One hundred thirteen autopsy protocols were examined. Radiographic correlation was obtained in 60 of these cases. Autopsy pulmonary findings included hemorrhage in 74% of the cases, infectious infiltrates in 67%, edema or congestion in 57%, and leukemic infiltration in 26%. Only 5% of the chest radiographs were normal. Alveolar or interstitial abnormalities were identified in 90%, pleural effusion in 40%, and lymphadenopathy in 17%. Correlation demonstrated pulmonary infection to be by far the most common cause of radiographic opacity. Because of its frequent occurrence, high associated mortality, and potential reversibility, pneumonia must always be considered first in the differential diagnosis of radiographic opacity in these patients.
对成年白血病患者进行了一项影像学与病理学相关性研究，以确定胸部白血病累及及相关并发症的发生率和影像学表现。检查了113份尸检报告。其中60例获得了影像学相关性。尸检肺部发现包括74%的病例有出血，67%有感染性浸润，57%有水肿或充血，26%有白血病浸润。只有5%的胸部X线片正常。90%发现肺泡或间质异常，40%有胸腔积液，17%有淋巴结病。相关性研究表明，肺部感染是影像学opacity最常见的原因。由于其频繁发生、高相关死亡率和潜在的可逆性，在这些患者影像学opacity的鉴别诊断中，肺炎必须始终首先考虑。
