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犬薄束核中轴突和轴突终末的改变。

Altered axons and axon terminals in the nucleus gracilis of the dog.

作者信息

Gavelová M, Badonic T, Mitro A

出版信息

J Hirnforsch. 1983;24(4):399-404.

PMID:6643992
Abstract

Altered axons and axon terminals in the nucleus gracilis o the dogs were followed by means of electron microscopy. The axon terminals with characteristic ultrastructure were accompanied by synapses with altered presynaptic part. The changes of the presynaptic part were expressed by the evident decrease in synaptic vesicle number, hyperplasia of smooth endoplasmic reticulum and by abnormal mitochondrial figures. The altered axons measuring 14,6 micrometers in average contained hyperplastic and quite often dilated smooth endoplasmic reticulum as well as multiplied microtubular profiles. The mitochondria of the altered axons were characterized by the different degree of degeneration. The above mentioned structures in synapses as well as in axoplasma of the nucleus gracilis were found in the dogs of both sexes.

摘要

通过电子显微镜观察犬薄束核中轴突和轴突终末的变化。具有特征性超微结构的轴突终末伴有突触前部分改变的突触。突触前部分的变化表现为突触小泡数量明显减少、滑面内质网增生以及线粒体形态异常。平均直径为14.6微米的改变轴突含有增生且常扩张的滑面内质网以及增多的微管轮廓。改变轴突的线粒体具有不同程度的变性。上述突触以及薄束核轴浆中的结构在雌雄犬中均有发现。

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引用本文的文献

1
Diminished retrograde transport causes axonal dystrophy in the nucleus gracilis. Electron- and light-microscopic study.逆行运输减少导致薄束核轴突营养不良。电子显微镜和光学显微镜研究。
Acta Neuropathol. 1985;68(2):93-100. doi: 10.1007/BF00688629.