Khvatova E M, Lavrovskiĭ S N
Vopr Med Khim. 1978 Jan-Feb;24(1):31-5.
Spectrum of LDH isozymes and their activity were compared in animal brain tissue under circulatory and hypoxic forms of hypoxia. Dynamics and manifestation of alterations observed correlated primarily with the type of oxygen deficiency as well as with its severity and length of action. Development of oxygen deficiency in brain tissue was accompanied by increase in total LDH activity and by elevation in content of M-subunits, typical for "anaerobic" spectrum of LDH isozymes, with simultaneous decrease in amount of H-subunits.
比较了循环性缺氧和低张性缺氧条件下动物脑组织中乳酸脱氢酶（LDH）同工酶谱及其活性。观察到的变化动态和表现主要与缺氧类型、缺氧严重程度及其作用时长相关。脑组织中缺氧的发展伴随着LDH总活性的增加以及M亚基含量的升高，M亚基是LDH同工酶“厌氧”谱的典型特征，同时H亚基的量减少。
