[实验性葡萄球菌感染中心肌、肾脏及血清同工酶的活性]
[Activity of myocardial, kidney and serum isoenzymes in experimental staphylococcal infection].
作者信息
Kashkin K P, Nikiforova N A
出版信息
Vopr Med Khim. 1978 Jan-Feb;24(1):35-42.
Alteration in activity and spectrum of multiple forms of some enzymes were studied in rat blood serum, myocardium and kidney cells in dynamics of staphylococcal infection as well as after administration of exo- and intracellular protein of staphylococci into animals. In the infection intracellular distribution of enzymes was impared in animal tissues studied and "tissue" isoforms of enzymes were accumulated in blood. Staphylococcal exo- and intracellular substances were found to effect dissimilarly on spectrum and activity of isoenzymes from rat kydney, myocardium and blood serum.
在葡萄球菌感染的动态过程中以及向动物体内注射葡萄球菌的胞外和胞内蛋白后，研究了大鼠血清、心肌和肾细胞中某些酶的多种形式的活性和谱的变化。在感染过程中，所研究的动物组织中酶的细胞内分布受到损害，并且酶的“组织”同工型在血液中积累。发现葡萄球菌的胞外和胞内物质对大鼠肾脏、心肌和血清中同工酶的谱和活性有不同的影响。
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