Shinozaki N, Sakamoto A, Kasai N, Uchida M, Sakurai K
Gan No Rinsho. 1983 Oct;29(12):1385-91.
The characteristics of multiple primary carcinomas associated with thyroid carcinoma were studied in 35 patients (35/362; 9.7%) who met the clinicopathological criteria of Warren and Gate. The frequency of the association was similar in papillary and follicular thyroid carcinomas. The average patient age at the time of initial carcinoma detection was 60.3 years for males and 51.5 years for females. The most frequent sites of the associated cancers were breast, uterine cervix and uterine body in females, and stomach and larynx in males. Patients should be followed closely for recurrence and second cancer detection in the early stage.
对35例（35/362；9.7%）符合沃伦和盖特临床病理标准的甲状腺癌相关多原发性癌的特征进行了研究。甲状腺乳头状癌和滤泡状癌的关联频率相似。男性首次发现癌症时的平均年龄为60.3岁，女性为51.5岁。相关癌症最常见的部位，女性为乳腺、子宫颈和子宫体，男性为胃和喉。应密切随访患者，以便早期发现复发和第二种癌症。
