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[高功率脉冲激光辐射对实验性肿瘤转移的影响]

[Effect of high-power pulse laser radiation on experimental tumor metastasis].

作者信息

Moskalik K G, Lazo V V, Kozlov A P, Il'chenko A M, Serebriakov V A

出版信息

Vopr Onkol. 1978;24(5):41-5.

PMID:664534
Abstract

Under study was the effect of the energy density and pulse duration of laser radiation on metastasization of Lewis carcinoma and melanoma B16. It was shown that laser irradiation of blastomas, the energy density of the former not exceeding 400 joule/cm2 and the pulse duration being 1 msec, not only fails to contribute to tumor proliferation but, on the contrary, somewhat reduces the number of pulmonary metastases. The phenomenon of such kind is observed in simultaneous rise of the energy density up to 800 joule/cm2 and lengthening of the pulse up to 6 msec.

摘要

正在研究激光辐射的能量密度和脉冲持续时间对Lewis癌和黑色素瘤B16转移的影响。结果表明,对母细胞瘤进行激光照射,前者能量密度不超过400焦耳/平方厘米,脉冲持续时间为1毫秒,不仅不会促进肿瘤增殖,反而会在一定程度上减少肺转移瘤的数量。当能量密度同时提高到800焦耳/平方厘米且脉冲延长到6毫秒时,会观察到这种现象。

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