Boyes D A
Prog Clin Biol Res. 1983;132E:483-93.
The screening program for cervix cancer in the Province of British Columbia appears to have reached a stable state. It has achieved a reduction in incidence of clinical squamous carcinoma in women over 20 of about 75% and reduction in mortality of about two thirds. Data has been presented to suggest that no further improvement in these rates should be forthcoming in a voluntary program such as ours. There has been a real increase in the numbers of in situ carcinomas found in our population but despite this increase clinical invasive carcinoma has not risen and we attribute this to the success of the program in intercepting disease before it becomes invasive. Endometrial carcinoma has not increased in our population and we do not feel that the current methods for early detection of this disease are applicable to a province-wide study. We intend to continue to emphasize the earliest possible investigation of abnormal peri- and postmenopausal bleeding by fractional curettage, as our mainstay of detection.
不列颠哥伦比亚省的宫颈癌筛查项目似乎已达到稳定状态。该项目使20岁以上女性临床鳞状细胞癌的发病率降低了约75%,死亡率降低了约三分之二。已有数据表明,像我们这样的自愿性项目,这些比率不会再有进一步改善。我们人群中发现的原位癌数量确实有所增加,但尽管有这种增加,临床浸润癌并未上升,我们将此归因于该项目在疾病发展为浸润性之前就成功拦截了疾病。我们人群中的子宫内膜癌没有增加,并且我们认为目前这种疾病的早期检测方法不适用于全省范围的研究。我们打算继续强调通过分段刮宫对绝经前后异常出血进行尽可能早的检查,将其作为我们检测的主要手段。