Frühwald F, Kovarik J, Neuhold A, Seidl G
Radiologe. 1983 Nov;23(11):529-31.
The most important factor that appears to be associated with soft-tissue calcifications in uremics is the increase of serum-phosphate levels, especially if the calcium-phosphate product exceeds the value of 75 (concentrations in mg/dl) [6]. In contrast to previous years tumoral paraarticular calcinosis is now rarely seen because much more attention has been paid to the prevention of hyperphosphatemia and because of pharmacological improvement of phosphate binding agents. Therefore, the level of serum phosphate in hemodialysed patients primarily depends on the patients adherence to the low phosphate diet and compliance with the phosphate binding therapy [4, 8]. We want to report of a patient on chronic intermittent hemodialysis who developed tremendous paraarticular soft tissue calcifications during a short period of time due to uncontrolled hyperphosphatemia despite correct intake of phosphate binding compounds.
与尿毒症患者软组织钙化似乎相关的最重要因素是血清磷酸盐水平的升高,尤其是当钙磷乘积超过75(单位:mg/dl)时[6]。与前些年相比,肿瘤性关节旁钙化现在很少见,这是因为对高磷血症的预防给予了更多关注,也由于磷酸盐结合剂在药理学上的改进。因此,血液透析患者的血清磷酸盐水平主要取决于患者对低磷饮食的依从性以及对磷酸盐结合治疗的依从性[4, 8]。我们想要报告一位接受慢性间歇性血液透析的患者,尽管正确摄入了磷酸盐结合化合物,但由于高磷血症未得到控制,在短时间内出现了大量关节旁软组织钙化。