Blaschke U, Wendel H, Nagel K H
Z Gesamte Inn Med. 1978 Apr 1;33(7):207-10.
On the basis of two own observations the clinical and radiological routine methods undergo a critical judgment concerning their valency for the diagnosis of Wegener's granulomatosis. The two patients showed the picture of a severe septical disease with high fever and expressed inflammatory changes of the biological reactions. In the first observation a pulmonary round focus and terminally the renal failure, in the second case severe inflammatory changes of the lungs without response to antibiotic therapy were in the foreground. The appearance of this disease as generalized vasculitis is conditioned by the manifold clinical symptomatology and thus renders the diagnostics extraordinarily difficult. The simultaneous affection of the nasopharyngeal space, of the lung and the kidneys may be a guide for the diagnosis. The X-ray findings of the lung are not able to found sufficiently the diagnosis.
基于两项自身观察，对临床和放射学常规方法在韦格纳肉芽肿诊断中的效价进行了批判性评判。两名患者均表现出严重败血症疾病的症状，伴有高热，并出现生物反应的明显炎症变化。在第一例观察中，肺部出现圆形病灶，最终发展为肾衰竭；在第二例中，肺部严重炎症变化对抗生素治疗无反应是主要表现。这种疾病作为全身性血管炎出现，其临床表现多样，因此诊断极具难度。鼻咽部、肺部和肾脏同时受累可能有助于诊断。肺部的X线检查结果不足以确诊。
