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脂磷壁酸在马链球菌黏附上皮细胞过程中的作用。

The role of lipoteichoic acids on the adherence of Streptococcus equi to epithelial cells.

作者信息

Srivastava S K, Barnum D A

出版信息

Vet Microbiol. 1983 Oct;8(5):485-92. doi: 10.1016/0378-1135(83)90042-1.

DOI:10.1016/0378-1135(83)90042-1
PMID:6649407
Abstract

The effect of the presence of lipoteichoic acids (LTA) on a strain of Streptococcus equi was investigated. The LTA were extracted in a crude form from the S. equi strain and were found to sensitize sheep red blood cells so that they agglutinated with antibodies specific to purified LTA of group A streptococci. The crude LTA preparation was also able to inhibit the specific haemagglutination reaction involving group A streptococcal LTA and LTA antibodies. Neither the purified LTA from group A streptococci nor the anti-LTA serum interfered with the adherence of S. equi to equine epithelial cells.

摘要

研究了脂磷壁酸(LTA)的存在对马链球菌菌株的影响。从马链球菌菌株中以粗制形式提取LTA,发现其可使绵羊红细胞致敏,从而使其与A组链球菌纯化LTA的特异性抗体发生凝集。粗制LTA制剂还能够抑制涉及A组链球菌LTA和LTA抗体的特异性血凝反应。A组链球菌的纯化LTA和抗LTA血清均不干扰马链球菌对马上皮细胞的黏附。

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