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[实验性心肌梗死时肝脏与血清中乳酸脱氢酶活性及其同工酶组成的相关性]

[Correlation of lactate dehydrogenase activity and its isoenzyme composition in the liver and blood serum in experimental myocardial infarction].

作者信息

Prashkiavichius A K, Lukoshiavichius L Iu, Grigaliunene V I, Shatinskene R R

出版信息

Vopr Med Khim. 1983 Sep-Oct;29(5):58-62.

PMID:6649534
Abstract

After ligation of coronary artery an initial increase in LDH activity in liver tissue was followed by its decrease. Minimal enzymatic activity in liver tissue correlated with maximal activity in blood serum within 1-3 days. Among LDH isoenzymes the "pure" fractions were most markedly altered: LDH1 was decreased in liver tissue and increased in blood serum, LDH5 was increased in the both tissues within later periods after normalization of total activity. Enzymatic activity of LDH, LDH1 and LDH5 was shown to correlate in liver tissue and blood serum.

摘要

冠状动脉结扎后,肝组织中乳酸脱氢酶(LDH)活性先升高后降低。在1 - 3天内,肝组织中的最低酶活性与血清中的最高活性相关。在LDH同工酶中,“纯”组分变化最为明显:肝组织中LDH1降低,血清中LDH1升高,在总活性恢复正常后的后期,两种组织中的LDH5均升高。结果表明,肝组织和血清中LDH、LDH1和LDH5的酶活性具有相关性。

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[Correlation of lactate dehydrogenase activity and its isoenzyme composition in the liver and blood serum in experimental myocardial infarction].[实验性心肌梗死时肝脏与血清中乳酸脱氢酶活性及其同工酶组成的相关性]
Vopr Med Khim. 1983 Sep-Oct;29(5):58-62.
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Myocardial contractile efficiency increases in proportion to a fetal enzyme shift in chronically infarcted rat hearts.在慢性梗死大鼠心脏中,心肌收缩效率与胎儿期酶的转变成比例增加。
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Adjustments of serum lactate dehydrogenase isoenzymes and their significance in monitoring the treatment in patients with tubercular pyothorax.血清乳酸脱氢酶同工酶的调整及其在结核性脓胸患者治疗监测中的意义
Indian J Clin Biochem. 2008 Apr;23(2):181-5. doi: 10.1007/s12291-008-0040-4. Epub 2008 Jun 11.