Demidov V P, Agranat V Z, Ol'shanskiĭ V O, Babakulyeva D, Voronetskiĭ I B
Vopr Onkol. 1983;29(11):27-32.
Levels of thyroid hormones and thyrotropin in 58 cases of adenoma and 86 cases of cancer of the thyroid gland were assayed radioimmunologically. Secretory function of the thyroid gland was inhibited in cancer patients and increased in adenoma group. Due to feedback, peripheral blood--thyrotropin levels were lowered in adenoma patients and raised in the cancer group. The hormonal disturbances were not identical in males and females; they were more pronounced in patients with disseminated tumor aged 46-55. The latter finding points to a decline in thyroid function with aging.
采用放射免疫法检测了58例甲状腺腺瘤及86例甲状腺癌患者的甲状腺激素和促甲状腺激素水平。甲状腺癌患者的甲状腺分泌功能受到抑制，而腺瘤组则增强。由于反馈作用，腺瘤患者外周血促甲状腺激素水平降低，而癌组升高。激素紊乱在男性和女性中并不相同；在46 - 55岁的播散性肿瘤患者中更为明显。后一发现表明甲状腺功能随年龄增长而下降。
