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[慢性失血性缺铁性贫血中的淋巴细胞变化]

[Lymphocyte changes in chronic posthemorrhagic iron-deficiency anemia].

作者信息

Apostolov P, Atanasova L, Stamenova T, Dimitrov V, Prokopanov Kh

出版信息

Vutr Boles. 1983;22(3):95-9.

PMID:6649591
Abstract

Ninety patients with chronic posthemorrhagic iron deficiency anemia were examined, looking for morphological and functional deviations in peripheral blood lymphocytes. Reduced blast transformation of lymphocytes was found under the effect of phytohemagglutinin and as improvement - by the treatment with iron-containing preparations. No reduction was established of T-lymphocytes, immunoglobulins as well as a change in the ultrastructure of lymphocyte mitochondria. The role of iron deficiency is discussed in connection with the phenomena observed as well as the enhanced susceptibility to acute respiratory infections.

摘要

对90例慢性出血后缺铁性贫血患者进行了检查,以寻找外周血淋巴细胞的形态和功能异常。发现淋巴细胞在植物血凝素作用下的原始细胞转化降低,而用含铁制剂治疗后有所改善。未发现T淋巴细胞、免疫球蛋白减少以及淋巴细胞线粒体超微结构改变。结合观察到的现象以及对急性呼吸道感染易感性增加,讨论了缺铁的作用。

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