Stauffer U G
Z Kinderchir. 1983 Oct;38(5):286-9. doi: 10.1055/s-2008-1059989.
The transplantation of small intestine is still an experimental therapy. In men, small intestinal transplantation has not yet been successful. Although the technical problems of small intestinal transplantation and monitoring of the grafts have been resolved in animal experiments and a transplantation model has been prepared, survival time of the grafts has been insufficient so far. The introduction of Cyclosporin A as immunosuppressive drug may lead to a dramatic change in the attitude towards small intestinal transplantation. Preliminary results in experimental studies in dogs and piglets with long-term survival of recipients and grafts are very encouraging.
小肠移植仍然是一种实验性治疗方法。在人类中,小肠移植尚未成功。尽管在动物实验中已经解决了小肠移植及移植物监测的技术问题,并建立了移植模型,但到目前为止,移植物的存活时间仍不足够。环孢素A作为免疫抑制药物的引入可能会导致对小肠移植态度的巨大改变。在犬和仔猪实验研究中获得的受者和移植物长期存活的初步结果非常令人鼓舞。