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兔直肠肌间神经丛电刺激后肛门内括约肌的反应

Internal anal sphincter response after electrical stimulation of the rectal myenteric nerve plexus in the rabbit.

作者信息

Frenckner B

出版信息

Z Kinderchir. 1983 Oct;38(5):290-2. doi: 10.1055/s-2008-1059990.

DOI:10.1055/s-2008-1059990
PMID:6649899
Abstract

The internal anal sphincter response to electrical stimulation of the rectal mucosa was studied in six rabbits. The anal canal was dissected free and then opened with an anterior, longitudinal incision to yield a flat sphincter preparation. After the external sphincter had been paralysed, isometric recordings of internal sphincter activity were performed. Electrical stimulation applied to the rectal mucosa elicited sphincter relaxations in all rabbits. Division of the gut beneath the point of stimulation blocked the response, as did local submucous anaesthesia. The results show (1) that electrical stimulation of the rectum can elicit internal sphincter relaxation, and (2) that the response is mediated via the myenteric and submucosal nerve plexuses.

摘要

在六只兔子身上研究了肛门内括约肌对直肠黏膜电刺激的反应。将肛管游离后,从前侧做纵向切口打开,制成扁平的括约肌标本。在外括约肌麻痹后,进行肛门内括约肌活动的等长记录。对直肠黏膜施加电刺激可使所有兔子的括约肌松弛。在刺激点下方切断肠道会阻断该反应,局部黏膜下麻醉也会如此。结果表明:(1)直肠电刺激可引起肛门内括约肌松弛;(2)该反应是通过肌间神经丛和黏膜下神经丛介导的。

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