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多发性肌炎的食管动力障碍。一项前瞻性研究。

The esophageal motility disorder of polymyositis. A prospective study.

作者信息

Jacob H, Berkowitz D, McDonald E, Bernstein L H, Beneventano T

出版信息

Arch Intern Med. 1983 Dec;143(12):2262-4.

PMID:6651419
Abstract

A prospective study of 12 patients with the diagnosis of polymyositis or dermatomyosiois was initiated to determine the characteristics of the esophageal manometric patterns in this group. All of the patients were women between the ages of 30 to 80 years and met three of four of Bohan's diagnostic criteria for these diseases. The patients' conditions were classified according to Rose and Walton's muscle weakness index. Almost two thirds of our patients exhibited distal esophageal dysfunction by manometry. Based on our roentgenographic and manometric data, we conclude that in addition to the well-described abnormalities in the striated portion of the esophagus, smooth-muscle dysfunction occurs with a high frequency in this patient population.

摘要

开展了一项针对12例诊断为多发性肌炎或皮肌炎患者的前瞻性研究,以确定该组患者食管测压模式的特征。所有患者均为30至80岁的女性,符合博汉氏这些疾病诊断标准中的四项标准中的三项。根据罗斯和沃尔顿的肌肉无力指数对患者的病情进行分类。通过测压,几乎三分之二的患者表现出食管远端功能障碍。基于我们的X线和测压数据,我们得出结论,除了食管横纹肌部分已被充分描述的异常外,平滑肌功能障碍在该患者群体中也很常见。

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