关于酪氨酸碘化的机制。
On the mechanism of iodination of tyrosine.
作者信息
Dunford H B, Ralston I M
出版信息
Biochem Biophys Res Commun. 1983 Oct 31;116(2):639-43. doi: 10.1016/0006-291x(83)90572-7.
PMID:6651828
Abstract
Existing data contain proof that the iodinating species of tyrosine and its derivatives contained in mixtures of iodine and iodide is hypoiodous acid, HOI. It appears likely that the peroxidase-catalyzed iodination reaction with hydrogen peroxide, tyrosine or a tyrosine derivative and either iodide or iodine as substrates involves enzyme-activated HOI.
摘要
现有数据证明，碘与碘化物混合物中所含酪氨酸及其衍生物的碘化物质是次碘酸（HOI）。过氧化物酶催化的以过氧化氢、酪氨酸或酪氨酸衍生物以及碘化物或碘为底物的碘化反应，似乎涉及酶激活的次碘酸。
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