特应性皮炎中针对膳食蛋白质的沉淀素

Precipitins to dietary proteins in atopic eczema.

作者信息

Barnetson R S, Drummond H, Ferguson A

出版信息

Br J Dermatol. 1983 Dec;109(6):653-5. doi: 10.1111/j.1365-2133.1983.tb00544.x.

DOI:10.1111/j.1365-2133.1983.tb00544.x

PMID:6652040

Abstract

Precipitating antibodies to foods have been assayed in three groups of patients with atopy. Forty-five per cent of patients with atopic eczema and IgE-mediated food allergy had precipitins to foods in their serum compared with only 15% of patients with atopic eczema without evidence of food allergy, and 16% of patients with atopic asthma and/or rhinitis. It is likely that this results from increased intestinal permeability in the group with eczema and food allergy.

摘要

对三组特应性疾病患者检测了食物沉淀抗体。在患有特应性皮炎且有IgE介导的食物过敏的患者中，45%的人血清中有食物沉淀素，相比之下，没有食物过敏证据的特应性皮炎患者中只有15%，患有特应性哮喘和/或鼻炎的患者中有16%有食物沉淀素。这可能是由于患有湿疹和食物过敏的人群肠道通透性增加所致。