Oishi R, Nishibori M, Saeki K
Brain Res. 1983 Nov 28;280(1):172-5. doi: 10.1016/0006-8993(83)91188-5.
Regional histamine (HA) and tele-methylhistamine (t-MH) contents were determined in the rat, mouse and guinea-pig brain. The highest HA and t-MH levels were found in the hypothalamus of all species. Fairly high t-MH levels were observed in the amygdala of all species and in the guinea-pig hippocampus. The t-MH/HA ratio was higher in the regions of the telencephalon than in the diencephalon and brainstem. The cerebellum and spinal cord showed extremely low t-MH/HA ratios. These results suggest higher histaminergic neuronal activities in the hypothalamus and some regions of the telencephalon than in other parts of the brain.
测定了大鼠、小鼠和豚鼠大脑中局部组胺（HA）和甲基组胺（t-MH）的含量。在所有物种的下丘脑发现了最高的HA和t-MH水平。在所有物种的杏仁核以及豚鼠的海马体中观察到相当高的t-MH水平。端脑区域的t-MH/HA比值高于间脑和脑干区域。小脑和脊髓的t-MH/HA比值极低。这些结果表明，下丘脑和端脑的某些区域比大脑其他部位具有更高的组胺能神经元活性。
