Bear J C
Clin Genet. 1983 Dec;24(6):407-12. doi: 10.1111/j.1399-0004.1983.tb00095.x.
Examination of fetal wastage data for a large collection of CL +/- P and CP sibships reported previously (Bear 1978) does not indicate the frequency of recognized abortion to be higher in the sibships of CL + P vs CL index cases, female vs male CL +/- P index cases, bilateral vs unilateral CL +/- P index cases, female bilateral CL +/- P index cases vs male unilateral CL +/- P index cases, or male vs female CP index cases. These observations fail to confirm those reported by Dronamraju (Dronamraju et al. 1982, Dronamraju & Bixler 1983a, b), and provide no evidence of a positive relation between degree of liability to facial cleft malformation and fetal mortality.
对先前报告的大量CL +/- P和CP同胞组的胎儿流失数据进行检查（贝尔，1978年），结果表明，在CL + P同胞组与CL指数病例的同胞组、女性与男性CL +/- P指数病例、双侧与单侧CL +/- P指数病例、女性双侧CL +/- P指数病例与男性单侧CL +/- P指数病例，或男性与女性CP指数病例中，已确认的流产频率并无更高。这些观察结果未能证实德罗纳姆拉朱所报告的情况（德罗纳姆拉朱等人，1982年；德罗纳姆拉朱与比克斯勒，1983年a、b），也未提供面部裂畸形易感性程度与胎儿死亡率之间存在正相关关系的证据。
