McKeown-Eyssen G E, Ruedy J
Clin Invest Med. 1983;6(3):161-9.
The prevalence of neurological abnormality was determined among Cree Indians of northern Quebec who were exposed to methylmercury through contamination of local fish. A medical team examined each subject, without knowledge of the subjects' methylmercury exposure, and assessed nystagmus, co-ordination and gait, tremor, movements and reflexes, sensation, stereognosis, 2 point discrimination, visual fields and hearing. Tremor, incoordination and abnormal reflexes were the most prevalent neurological abnormalities, but other major manifestations of methylmercury toxicity (impairment of peripheral sensation, astereognosis and concentric constriction of visual fields) were seen infrequently. Abnormalities in Quebec were much less severe than in previous reported outbreaks of methylmercury poisoning. Since no single clinical syndrome is pathognomonic of methylmercury poisoning, the presence of neurological abnormality does not establish that it is causally related to methylmercury exposure.
在魁北克北部因当地鱼类受污染而接触甲基汞的克里族印第安人中，对神经异常的患病率进行了测定。一个医疗团队在不了解受试者甲基汞接触情况的前提下对每位受试者进行了检查，并评估了眼球震颤、协调能力和步态、震颤、运动和反射、感觉、实体觉、两点辨别觉、视野和听力。震颤、不协调和异常反射是最常见的神经异常，但甲基汞中毒的其他主要表现（外周感觉受损、实体觉缺失和视野向心性收缩）则较少见。魁北克的异常情况比之前报道的甲基汞中毒暴发要轻得多。由于没有单一的临床综合征是甲基汞中毒所特有的，神经异常的存在并不能确定其与甲基汞接触有因果关系。
