Jørgensen O S, Møller M
Dev Biol. 1983 Dec;100(2):275-86. doi: 10.1016/0012-1606(83)90222-1.
The localization of an antigen immunochemically crossreactive with the rat brain interneuronal adhesion molecule, D2-protein, has in testis been demonstrated by immunoelectrophoresis and immunocytochemistry. This D2-like antigen is localized to spermatids and residual bodies in testis, but it is absent both from spermatogonia and mature spermatozoa and from Sertoli cells. By immunoperoxidase electronmicroscopy D2-like antigen was observed in the head region posterior to the acrosomal membrane of late spermatids. In the nervous system D2-protein is involved in interneuronal adhesion. It is suggested that D2-like antigen in testis may be involved in a similar adhesion between late spermatids and Sertoli cells during spermiation.
通过免疫电泳和免疫细胞化学方法已证实，睾丸中存在一种与大鼠脑内神经元粘附分子D2蛋白发生免疫化学交叉反应的抗原。这种D2样抗原定位于睾丸中的精子细胞和残余小体，但精原细胞、成熟精子以及支持细胞中均不存在。通过免疫过氧化物酶电子显微镜观察发现，晚期精子细胞顶体膜后方的头部区域存在D2样抗原。在神经系统中，D2蛋白参与神经元间的粘附。有人提出，睾丸中的D2样抗原可能在精子释放过程中参与晚期精子细胞与支持细胞之间的类似粘附作用。
