di Costanzo J, Martin J, Cano N, Cros R C, Sastre B, Noirclerc M, Pélissier G
Gastroenterol Clin Biol. 1983 Nov;7(11):851-6.
It is difficult to select and combine the nutritional parameters most useful in predicting the outcome of major gastrointestinal surgery. The aim of this study was to define retrospectively a multifactorial prognostic nutritional index adapted to this purpose. Seventy-eight patients on whom one or more total or partial visceral resection were performed in nonemergency conditions were included in this study. Statistical analysis was carried out to determine correlations between the preoperative nutritional parameters and the postoperative complications such as: a) wound rupture and anastomotic leakage; b) severe sepsis; c) death. Delayed hypersensitivity, assessed as normal or abnormal, together with plasmatic albumin and transferrin levels, the thresholds of which were respectively determined at 35 g/l and 2.2 g/l, were selected as the factors with the greatest predictive value. For the prognosis of postoperative severe complications and death, the sensitivity and specificity of an index using the association of these three parameters were respectively 82.7 p. 100 and 51 p. 100 with positive and negative predictive values of 50 p. 100 and 83.3 p. 100.
选择并组合对预测重大胃肠道手术结果最有用的营养参数并非易事。本研究的目的是回顾性地定义一个适用于此目的的多因素预后营养指数。本研究纳入了78例在非紧急情况下接受了一次或多次全部或部分内脏切除术的患者。进行了统计分析,以确定术前营养参数与术后并发症之间的相关性,这些并发症包括:a)伤口破裂和吻合口漏;b)严重脓毒症;c)死亡。将评估为正常或异常的迟发型超敏反应以及血浆白蛋白和转铁蛋白水平(其阈值分别确定为35 g/l和2.2 g/l)选为具有最大预测价值的因素。对于术后严重并发症和死亡的预后,使用这三个参数联合的指数的敏感性和特异性分别为82.7%和51%,阳性预测值和阴性预测值分别为50%和83.3%。