Steinschneider A
Am J Dis Child. 1978 Jul;132(7):688-91. doi: 10.1001/archpedi.1978.02120320048011.
A standard lead II ECG was recorded during either the first or the fourth week of life or at both ages from 30 neonates whose sibling had died of the sudden infant death syndrome (SIDS). Electrocardiographic recordings also were obtained from 75 control neonates and from 52 adults who had had an infant who died of SIDS. The neonatal data revealed that the QT interval, corrected for heart rate (QTC), was longest during NREM (vs rapid eye movement [REM]) sleep. Furthermore, the QTC interval was longer within the fourth week than in the first week of life. However, the QTC interval of siblings of SIDS victims did not differ from that of the control infants, nor did the QT interval of parents of SIDS victims differ from published normal values. One neonate who subsequently died of SIDS did not have an abnormally long QTC interval. These data do not support the hypothesis that genetically determined prolongation of the QT interval plays a major role in SIDS.
对30名兄弟姐妹死于婴儿猝死综合征（SIDS）的新生儿，在其出生后第一周或第四周或两个年龄段都记录了标准II导联心电图。还从75名对照新生儿和52名有婴儿死于SIDS的成年人那里获得了心电图记录。新生儿数据显示，经心率校正的QT间期（QTC）在非快速眼动（NREM）睡眠期间最长（与快速眼动[REM]睡眠相比）。此外，QTC间期在出生后第四周比第一周长。然而，SIDS受害者兄弟姐妹的QTC间期与对照婴儿的没有差异，SIDS受害者父母的QT间期也与已公布的正常数值没有差异。一名随后死于SIDS的新生儿没有QTC间期异常延长的情况。这些数据不支持QT间期的遗传决定延长在SIDS中起主要作用这一假说。
