Neville E, Walker A N, James D G
Q J Med. 1983 Autumn;52(208):525-33.
A computerised, retrospective study of 818 patients with sarcoidosis was analysed to study the prognosis of each individual manifestation of the disease. The good prognosis of erythema nodosum, acute arthritis and bilateral hilar lymphadenopathy was confirmed, though 16 per cent of patients presenting with erythema nodosum pursued a chronic course. Cor pulmonale and nephrocalcinosis reflected the poorest prognosis while lupus pernio and sarcoidosis of the mucosa of the upper respiratory tract rarely resolved. Bone sarcoidosis also implied chronicity but in four of 31 patients there was no clinical evidence of disease activity two years after the initial diagnosis, although naturally the bone radiograph was still abnormal. Hepatomegaly carried a worse prognosis than splenomegaly, or indeed, than the finding of pulmonary mottling without hilar glands--a stage three chest radiograph.
对818例结节病患者进行了一项计算机化回顾性研究，以探讨该疾病各临床表现的预后。结节性红斑、急性关节炎和双侧肺门淋巴结肿大预后良好，不过16%表现为结节性红斑的患者病程呈慢性。肺心病和肾钙质沉着症预后最差，而冻疮样狼疮和上呼吸道黏膜结节病很少缓解。骨结节病也意味着病程呈慢性，但在31例患者中有4例在初诊两年后无疾病活动的临床证据，尽管骨X线片仍异常。肝肿大比脾肿大预后更差，实际上，比无肺门淋巴结的肺部斑点状阴影（胸部X线片三期表现）预后更差。
