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通过唾液分析对体内碘-125污染情况的监测

[Monitoring of I-125 contamination in vivo by analysis of the saliva].

作者信息

Nishizawa K, Hamada N, Sakuma S

出版信息

Radioisotopes. 1983 Aug;32(8):364-71.

PMID:6658024
Abstract

Monitoring of workers who did iodination of protein was performed for 5 months on 10 persons. The activity in saliva was evaluated following the sun peak method by using a NaI(Tl) detector and a 400-channel analyzer. The concentration of 125I in saliva ranged 4.65 +/- 2.1 cBq (1.26 +/- 0.57 pCi)/ml to 135 +/- 2.7 cBq (36.45 +/- 0.73 pCi)/ml and the average was 20.8 +/- 1.9 cBq (5.62 +/- 0.51 pCi)/ml. The ratio of concentration in saliva to used activity ranged (2.2 +/- 0.64) X 10(-9) to (3.6 +/- 0.073) X 10(-8) and the average was (8.1 +/- 1.1) X 10(-9). The thyroidal uptake per iodination ranged 146 Bq (3.94 nCi) to 2700 Bq (72.9 nCi). The ratio of the uptake to the used activity ranged from 7.3 X 10(-5) to 5.4 X 10(-6). The thyroidal absorbed dose ranged from 378 microGy (37.8 mrad) to 4740 microGy (474 mrad). Monitoring of 125I-in saliva was proved to be a useful method to investigate the internal contamination of workers doing iodination.

摘要

对10名从事蛋白质碘化工作的工人进行了为期5个月的监测。使用碘化钠(铊)探测器和400通道分析仪,按照太阳峰法评估唾液中的放射性活度。唾液中125I的浓度范围为4.65±2.1贝克勒尔(1.26±0.57皮居里)/毫升至135±2.7贝克勒尔(36.45±0.73皮居里)/毫升,平均为20.8±1.9贝克勒尔(5.62±0.51皮居里)/毫升。唾液中浓度与使用的放射性活度之比范围为(2.2±0.64)×10−9至(3.6±0.073)×10−8,平均为(8.1±1.1)×10−9。每次碘化的甲状腺摄取量范围为146贝克勒尔(3.94纳居里)至2700贝克勒尔(72.9纳居里)。摄取量与使用的放射性活度之比范围为7.3×10−5至5.4×10−6。甲状腺吸收剂量范围为378微戈瑞(37.8毫拉德)至4740微戈瑞(474毫拉德)。监测唾液中的125I被证明是一种调查从事碘化工作的工人内部污染情况的有用方法。

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