Castronuovo S, Krohel G B, Kristan R W
Ann Ophthalmol. 1983 Aug;15(8):751-4.
We reviewed the records of 23 patients with systemic myasthenia gravis and blepharoptosis. The overall prognosis for improvement of blepharoptosis in these patients was favorable when multiple modes of therapy, including anticholinesterase medication, were used. Four of five patients with disabling blepharoptosis were stable enough after three to four years of their disease to consider corrective lid surgery. Two patients underwent levator resection with good results. Patients with systemic and ocular myasthenia gravis who are refractory to systemic therapy should be considered candidates for ptosis surgery when their blepharoptosis has been stable over a three- to four-year period.
我们回顾了23例全身性重症肌无力伴上睑下垂患者的病历。当采用包括抗胆碱酯酶药物在内的多种治疗方式时,这些患者上睑下垂改善的总体预后良好。五例严重上睑下垂患者中有四例在患病三到四年后病情稳定,足以考虑进行眼睑矫正手术。两名患者接受了提上睑肌切除术,效果良好。全身性和眼肌型重症肌无力患者若对全身治疗无效,当其睑下垂在三到四年内保持稳定时,应考虑作为睑下垂手术的候选者。