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[先天性假关节中骨组织发育的发育异常改变]

[Dysplastic changes in the development of bone tissue in congenital pseudarthrosis].

作者信息

Pavlova M N, Beliaeva A A, Gusev B V

出版信息

Arkh Patol. 1983;45(10):33-9.

PMID:6661072
Abstract

Angiographic examinations of shin blood vessels were carried out in 11 patients of 2 1/2 to 16 years with congenital false joints, and in 3 of these patients also pathomorphological and ultrastructural studies of the bone and cartilage tissue from the false joint area were performed. The deepest disorders of the blood supply were found at the level of the false joint. Dysplastic changes in the bone consisted in disorders of normal osteogenesis and atypical development of the cartilage, thinning of the bone structures, ultrastructural invalidity of osteocytes and insufficient mineral saturation of the organic matrix. Dystrophy of chondrocytes and deficient ultrastructure of collagen fibrills were noted.

摘要

对11例年龄在2岁半至16岁的先天性假关节患者的胫骨血管进行了血管造影检查,其中3例患者还对假关节区域的骨和软骨组织进行了病理形态学和超微结构研究。发现血液供应最深层的紊乱发生在假关节水平。骨发育异常改变包括正常骨生成紊乱、软骨非典型发育、骨结构变薄、骨细胞超微结构无效以及有机基质矿化不足。观察到软骨细胞营养不良和胶原纤维超微结构缺陷。

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