Bresolin A U
Arq Neuropsiquiatr. 1983 Dec;41(4):343-55. doi: 10.1590/s0004-282x1983000400004.
Our aim is to present the results obtained from the evaluation of the neurological examination as well as chemical and cytologic data from the CSF obtained at the admission and discharge of 255 children aged between zero and 12 years with a diagnosis of serogroup A meningococcal meningitis made at the Hospital Emilio Ribas in São Paulo, Brasil, in the years of 1976 and 1977. By the time of their admission, 27 patients (10,59%) showed positive neurologic findings besides meningeal signs. Seizures were the most common ones, with higher incidence in children under 13 months; ataxia, deafness, motor deficits, neuro-psychomotor involution, subdural effusions and disturbed behavior followed in that order. Subdural effusions were found only in those under 13 months. A fatal outcome was registered in eleven (4,31%) patients, of which nine died in the first 24 hours after admission. By the time of hospital discharge 14 patients (5,49%) had neurological abnormalities, deafness and ataxia being the most common ones, in the older patients. Under 13 months, developmental involution predominated. There is no need of CSF evaluation for antibiotic therapy interruption in patients with meningococcal meningitis.
我们的目的是呈现对255名年龄在0至12岁之间、于1976年和1977年在巴西圣保罗的埃米利奥·里巴斯医院被诊断为A群脑膜炎球菌性脑膜炎的儿童进行评估所获得的神经学检查结果以及脑脊液的化学和细胞学数据。入院时，27名患者（10.59%）除脑膜征外还表现出阳性神经学体征。癫痫发作最为常见，在13个月以下儿童中发病率更高；共济失调、耳聋、运动功能障碍、神经精神运动发育迟缓、硬膜下积液和行为障碍依次出现。硬膜下积液仅在13个月以下儿童中发现。11名患者（4.31%）出现了致命结局，其中9名在入院后24小时内死亡。出院时，14名患者（5.49%）存在神经学异常，耳聋和共济失调在年龄较大的患者中最为常见。在13个月以下儿童中，发育迟缓占主导。对于脑膜炎球菌性脑膜炎患者，中断抗生素治疗无需进行脑脊液评估。
