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[链球菌血清流行病学:三种方法的比较]

[Streptococcal seroepidemiology: comparison of 3 methods].

作者信息

Angela G C, Panarisi P, Tosco A

出版信息

Boll Ist Sieroter Milan. 1983 Sep 30;62(4):333-43.

PMID:6661292
Abstract

Streptococcal antibodies survey in adult population. In a series of 1609 hospitalized adult patients, without symptoms of acute or chronic streptococcal rheumatism, the level of antistreptococcal antibodies was measured, using three technical methods: the traditional one, i.e., antistreptolysim titer (ASLO); streptozyme titer (STZ) and the anti-C-polysaccharide technique (Microstreptokit, MSK); by the mutual comparison of these three antigens it was possible to ascertain some differences of the antibody response. In a mass survey it appears useful the use of two methods, i.e., ALSO and MSK; in investigations aiming at recognizing the cases with cardiac or rheumatic silent lesions the couple MSK-STZ appears to be more reliable. To ensure a more sure covering of the whole field of streptococcal silent infections, the three methods should be used together.

摘要

成人人群中的链球菌抗体调查。在1609例住院成年患者中,这些患者无急性或慢性链球菌性风湿病症状,采用三种技术方法测定抗链球菌抗体水平:传统方法,即抗链球菌溶血素滴度(ASLO);链激酶酶联免疫吸附试验滴度(STZ)和抗C多糖技术(微链球菌试剂盒,MSK);通过对这三种抗原的相互比较,可以确定抗体反应的一些差异。在大规模调查中,使用两种方法,即ASLO和MSK似乎是有用的;在旨在识别有心脏或风湿性隐匿性病变病例的调查中,MSK-STZ组合似乎更可靠。为了确保更全面地覆盖链球菌隐匿性感染的整个领域,应同时使用这三种方法。

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