Tumanov V P, Shimkevich L L, Muzykant L I, Gasanov T M, Sergel' O S
Biull Eksp Biol Med. 1983 Dec;96(12):107-10.
Morphological and cytological methods were used to study the healing of a burn wound in local isolation wards (an open treatment method) and under ointment bandages (a closed treatment method). Biopsy specimens and imprints from the burn wound surface were taken from 40 patients. During treatment in an abacterial medium, burn wound was rapidly decontaminated, which was a consequence of the appearance in wound exudate of segmented neutrophils with marked neutrophilic granularity. Granulation tissue was formed in the wound cavity at the 5th-7th day after the treatment commencement. During treatment under bandages wound decontamination was extremely slow. For a long time wound exudate shows the predominance of dystrophically changed neutrophils, while granulation tissue in the wound cavity if formed only at the 21st-24th day after the treatment commencement.
采用形态学和细胞学方法，研究了局部隔离病房（开放治疗法）和软膏绷带包扎（封闭治疗法）下烧伤创面的愈合情况。从40例患者身上采集了烧伤创面的活检标本和印记。在无菌培养基中治疗期间，烧伤创面迅速净化，这是由于伤口渗出物中出现了具有明显嗜中性粒细胞颗粒的分叶中性粒细胞。治疗开始后第5 - 7天，伤口腔内形成肉芽组织。在绷带包扎治疗期间，伤口净化极其缓慢。长时间内伤口渗出物显示出营养不良性改变的中性粒细胞占优势，而伤口腔内的肉芽组织仅在治疗开始后第21 - 24天才形成。
