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超声检查在梗阻性黄疸诊断中的应用

Ultrasonography in the diagnosis of obstructive jaundice.

作者信息

Lapis J L, Orlando R C, Mittelstaedt C A, Staab E V

出版信息

Ann Intern Med. 1978 Jul;89(1):61-3. doi: 10.7326/0003-4819-89-1-61.

Abstract

Forty-seven patients with cholestatic jaundice were evaluated for extrahepatic biliary obstruction by ultrasonic cholangiography and the results verified by contrast cholangiography, celiotomy, or autopsy. Sonograms were evaluated both with ("official" reading) and without ("blind" reading) clinical information. By showing dilated bile ducts, sonography correctly diagnosed extrahepatic obstruction in 26 of 30 patients on "official" reading and 23 of 30 on "blind" reading. In all 17 patients without extrahepatic obstruction, sonography revealed the absence of dilated bile ducts. Among patients with extrahepatic obstruction, those with larger bile ducts had higher bilirubin concentrations, longer duration of jaundice, and were more reliably detected by sonography. In these patients, 94% with total bilirubin concentration greater than 10 mg/dl were detected by sonography, while 47% with total bilirubin concentration less than 10 mg/dl were detected. Although we recognize the limited sensitivity of sonography in early extrahepatic obstruction, we find it to be a valuable screening test in cholestatic jaundice.

摘要

对47例胆汁淤积性黄疸患者进行超声胆管造影评估肝外胆管梗阻情况,并通过造影胆管造影、剖腹手术或尸检验证结果。超声图像在有临床信息(“正式”解读)和无临床信息(“盲法”解读)两种情况下进行评估。通过显示胆管扩张,超声检查在“正式”解读时正确诊断出30例患者中的26例肝外梗阻,“盲法”解读时为30例中的23例。在所有17例无肝外梗阻的患者中,超声检查显示无胆管扩张。在肝外梗阻患者中,胆管较大者胆红素浓度更高,黄疸持续时间更长,超声检查更容易检测到。在这些患者中,总胆红素浓度大于10mg/dl的患者94%可通过超声检查发现,而总胆红素浓度小于10mg/dl的患者仅47%可被检测到。虽然我们认识到超声检查在早期肝外梗阻中的敏感性有限,但我们发现它在胆汁淤积性黄疸中是一种有价值的筛查试验。

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