Jaeger N, Weissbach L, Kliems G
Chirurg. 1983 Dec;54(12):795-800.
This report concerns 18 patients with germinal testicular tumors in whom the resection of pulmonary metastases was indicated following resection of the primary tumor and combined cytostatic therapy. Nine patients underwent a retroperitoneal lymphadenectomy immediately after semi-castration. Upon follow-up examination, circular pulmonary foci were visualized by conventional films or computerized tomography. These patients developed pulmonary metastases on the average 8 months after the first operation (semi-castration and lymphadenectomy). Since 1978, a combined cytostatic treatment has preceded the lymphadenectomy and resection of parenchymal metastases. No evidence of disease (NED) could be achieved in 9 patients by resection of pulmonary metastases, with an average follow-up period of 30 months. The results in surgery of metastases are judged as the more advantageous, the longer the free interval is between initial disease onset and the occurrence of metastases.
本报告涉及18例原发性睾丸生殖细胞瘤患者,他们在切除原发性肿瘤并接受联合细胞抑制治疗后,需要切除肺部转移灶。9例患者在半侧睾丸切除术后立即接受了腹膜后淋巴结清扫术。在随访检查中,通过传统X线片或计算机断层扫描可发现肺部圆形病灶。这些患者在首次手术(半侧睾丸切除术和淋巴结清扫术)后平均8个月出现肺部转移。自1978年以来,在进行淋巴结清扫术和实质转移灶切除术之前先进行联合细胞抑制治疗。9例患者通过切除肺部转移灶达到无疾病证据(NED)状态,平均随访期为30个月。转移灶手术的结果被认为越有利,从疾病最初发作到转移灶出现的无瘤间期就越长。