Legros M, Castera D, Longuebray A, Blondel J H
Ann Otolaryngol Chir Cervicofac. 1978 Mar;95(3):205-10.
So-called "hyperfractionated" radiotherapy is aimed at obtaining synchronisation of tumour cells and to kill the cells synchronised in this way. The technique has been used now for approximately a year and a half in the treatment of 45 advanced or inoperable squamous carcinomas of the upper respiratory and digestive tract. The initial results are encouraging. Oncological sterilisation of the lesions is obtained at the price of actinic reactions which rapidly disappear, but also tumour necrosis, which indicates the need for review of the protocol.
所谓的“超分割”放疗旨在使肿瘤细胞同步化，并杀死以这种方式同步化的细胞。该技术现已用于治疗45例晚期或无法手术的上呼吸道和消化道鳞状癌，应用约一年半了。初步结果令人鼓舞。以迅速消失的光化反应为代价实现了病变的肿瘤学消除，但也出现了肿瘤坏死，这表明需要对方案进行审查。
