Morgan K G
J Physiol. 1983 Dec;345:135-47. doi: 10.1113/jphysiol.1983.sp014970.
Intracellular electrical recordings were made from arterioles and venules of the cat gastric submucosa. Spontaneous rhythmic fluctuations of the membrane potential were recorded in 54% of the venular preparations. Arteriolar cells showed no spontaneous activity. Excitatory junction potentials were recorded in arterioles but not venules after single shocks to the perivascular nerves. The amplitude of the excitatory junction potential was decreased in the presence of alpha-blockers. Repetitive stimulation of the perivascular nerve caused a biphasic electrical response of venular smooth muscle cells. The depolarizing component was decreased by alpha-adrenergic blockade and the hyperpolarizing component by beta-blockade. Venules contracted in response to smaller depolarizations than did arterioles. The voltage threshold for contraction of venular cells was similar to that for arteriolar cells but the venular cells were significantly more depolarized at rest than were the arteriolar cells. The difference in resting potential provides an explanation for the difference in sensitivity to electrical input.
在猫胃黏膜下层的小动脉和小静脉上进行了细胞内电记录。在54%的小静脉标本中记录到了膜电位的自发性节律波动。小动脉细胞未表现出自发性活动。对血管周围神经进行单次电击后，在小动脉中记录到兴奋性突触后电位，但在小静脉中未记录到。在α受体阻滞剂存在的情况下，兴奋性突触后电位的幅度降低。对血管周围神经进行重复刺激会引起小静脉平滑肌细胞的双相电反应。去极化成分通过α肾上腺素能阻断而降低，超极化成分通过β阻断而降低。与小动脉相比，小静脉对较小的去极化反应而收缩。小静脉细胞收缩的电压阈值与小动脉细胞相似，但小静脉细胞在静息时的去极化程度明显高于小动脉细胞。静息电位的差异为对电输入敏感性的差异提供了解释。
